Arsenal star Lacazette reportedly wants to leave the club having struggled for game time under Unai Emery so far.
The France international, who missed out on a place in Didier Deschamps’ World Cup winning squad, toiled under Arsene Wenger last season following his £52million arrival.
Arsenal signed him with the hope he could blossom into an heir to Thierry Henry but, with 17 goals to his name from just 42 Gunners appearances, a move away could be on the cards.
Reports have claimed Lacazette is mulling over his future with the 27-year-old approaching the peak years of his career.
And Coral have Lyon as favourites to sign the Arsenal striker.
The Ligue 1 giants have been priced at evens to re-sign him, despite allowing him to move to north London a year ago.
Lyon are set to invest in a new centre-forward with Mariano Diaz widely expected to return to Real Madrid.
PSG are in the running at 3-1 with fellow French side Marseille then priced at 5-1.
Real Madrid, despite their impending deal for Mariano, are at 8-1 with AC Milan at 12-1.
“Lacazette appears to have fallen down the pecking order at Arsenal this season therefore punters feel he could make a return to Lyon before the transfer window is closed,” said Coral’s John Hill.
Meanwhile, the Arsenal striker recently opened up on life under Emery, saying it was ‘different.’
He said: “The manager just told me to play my game and said we will win if I play well.
“There is a lot of difference under the new manager.
“You can’t really compare the two coaches – they are their own men when it comes to football.
“Even if the aim is still to play and hurt the opposition with the ball, there are some big differences.”
Should Arsenal cut Lacazette loose, they will be unable to sign a replacement.
The Premier League transfer window shut August 9 and the Gunners have allowed Lucas Perez to join West Ham on loan.